Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline TAP Air Portugal

The cheapest airline(s) flying from Chicago to Brussels is TAP Air Portugal.

  • TAP Air Portugal TAP Air Portugal
  • Scandinavian Airlines Scandinavian Airlines
  • Aer Lingus Aer Lingus
  • LOT Polish Airlines LOT Polish Airlines
  • Air Canada Air Canada
  • United Airlines United Airlines
  • Iberia Iberia
  • Air France Air France
  • KLM KLM
  • British Airways British Airways
Cheapest Month December

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Chicago to Brussels is December.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Chicago to Brussels is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

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      • Availability
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      • 17:55 ORD
        08:55 BRU
        8Hrs, 00m Direct
      • ORDChicago O'Hare International Airport 17:55 - BRU 08:55 8h Direct
      • ORDChicago O'Hare International Airport 17:55
      • BRUBrussels Airport 08:55
      • 8h
      • Direct
      • United Airlines (UA 972)Boeing Dreamliner Series 10
      • United Airlines (UA 972)
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        • S
      • Boeing Dreamliner Series 10
      • 18:00 ORD
        16:05 BRU
        15Hrs, 05m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 18:00 - BRU 16:05 15h 05m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 18:00
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 09:35
        BRUBrussels Airport 16:05
      • 15h 05m (5h 05m)
      • 1 Stop MUC · Munich 5h 05m
      • United Airlines (UA 953)Boeing Dreamliner Series 10
        Lufthansa (LH 2288)Airbus Industrie A320 Sharklets
      • United Airlines (UA 953)
        • -
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        • -
        • -
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        • S
      • 18:00 ORD
        16:05 BRU
        15Hrs, 05m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 18:00 - BRU 16:05 15h 05m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 18:00
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 09:35
        BRUBrussels Airport 16:05
      • 15h 05m (5h 05m)
      • 1 Stop MUC · Munich 5h 05m
      • United Airlines (UA 953)Boeing Dreamliner Series 10
        Lufthansa (LH 2288)Canadair Regional
      • United Airlines (UA 953)
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      • 18:00 ORD
        16:15 BRU
        15Hrs, 15m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 18:00 - BRU 16:15 15h 15m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 18:00
        MUCMunich International Airport 14:50
      • MUCMunich International Airport 09:35
        BRUBrussels Airport 16:15
      • 15h 15m (5h 15m)
      • 1 Stop MUC · Munich 5h 15m
      • United Airlines (UA 953)Boeing Dreamliner Series 10
        Lufthansa (LH 2288)Airbus Industrie A320 Sharklets
      • United Airlines (UA 953)
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      • 18:00 ORD
        16:15 BRU
        15Hrs, 15m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 18:00 - BRU 16:15 15h 15m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 18:00
        MUCMunich International Airport 14:50
      • MUCMunich International Airport 09:35
        BRUBrussels Airport 16:15
      • 15h 15m (5h 15m)
      • 1 Stop MUC · Munich 5h 15m
      • United Airlines (UA 953)Boeing Dreamliner Series 10
        Lufthansa (LH 2288)Canadair Regional
      • United Airlines (UA 953)
        • -
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        • -
      • 18:00 ORD
        16:05 BRU
        15Hrs, 05m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 18:00 - BRU 16:05 15h 05m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 18:00
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 09:35
        BRUBrussels Airport 16:05
      • 15h 05m (5h 05m)
      • 1 Stop MUC · Munich 5h 05m
      • United Airlines (UA 953)Boeing Dreamliner Series 10
        Lufthansa (LH 2288)Airbus
      • United Airlines (UA 953)
        • M
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        • -
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        • -
      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Airbus
        United Airlines (UA 210)Boeing 737 Max 9 Passenger
      • Lufthansa (LH 1012)
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      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Airbus
        United Airlines (UA 210)Boeing 737 Max 9 Passenger
      • Lufthansa (LH 1012)
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      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Airbus Industrie A320 Sharklets
        United Airlines (UA 210)Boeing 737 Max 9 Passenger
      • Lufthansa (LH 1012)
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      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Canadair Regional
        United Airlines (UA 210)Boeing 737 800
      • Lufthansa (LH 1012)
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      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Airbus
        United Airlines (UA 210)Boeing 737 800
      • Lufthansa (LH 1012)
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      • 13:00 FRA
        21:14 IAD
        12Hrs, 46m 1 Stop (BRU)
      • FRAFrankfurt International Airport 13:00 - IAD 21:14 12h 46m 1 Stop (BRU) Brussels
      • FRAFrankfurt International Airport 13:00
        ORDChicago O'Hare International Airport 18:14
      • BRUBrussels Airport 14:00
        IADWashington Dulles International Airport 21:14
      • 12h 46m (2h 01m)
      • 1 Stop BRU · Brussels 2h 01m
      • Lufthansa (LH 1012)Airbus
        United Airlines (UA 210)Boeing 737 900
      • Lufthansa (LH 1012)
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        • S
      • 18:30 ORD
        11:55 BRU
        10Hrs, 25m 1 Stop (KEF)
      • ORDChicago O'Hare International Airport 18:30 - BRU 11:55 10h 25m 1 Stop (KEF) Reykjavik
      • ORDChicago O'Hare International Airport 18:30
        KEFReykjavik Keflavik International Airport 07:35
      • KEFReykjavik Keflavik International Airport 06:40
        BRUBrussels Airport 11:55
      • 10h 25m (55m)
      • 1 Stop KEF · Reykjavik 55m
      • Icelandair (FI 852)Boeing 737 Max 9 Passenger
        Icelandair (FI 554)Boeing 737 Max 8 Passenger
      • Icelandair (FI 852)
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      • 18:30 ORD
        12:30 BRU
        11Hrs, 00m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 12:30 11h 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 11:30
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 12:30
      • 11h (1h 35m)
      • 1 Stop FRA · Frankfurt 1h 35m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1010)Airbus
      • United Airlines (UA 907)
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      • 18:30 ORD
        12:30 BRU
        11Hrs, 00m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 12:30 11h 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 11:30
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 12:30
      • 11h (1h 35m)
      • 1 Stop FRA · Frankfurt 1h 35m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1010)Airbus
      • United Airlines (UA 907)
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      • 18:30 ORD
        14:00 BRU
        12Hrs, 30m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 14:00 12h 30m 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 13:00
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 14:00
      • 12h 30m (3h 05m)
      • 1 Stop FRA · Frankfurt 3h 05m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1012)Airbus
      • United Airlines (UA 907)
        • M
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      • 18:30 ORD
        14:00 BRU
        12Hrs, 30m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 14:00 12h 30m 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 13:00
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 14:00
      • 12h 30m (3h 05m)
      • 1 Stop FRA · Frankfurt 3h 05m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1012)Canadair Regional
      • United Airlines (UA 907)
        • -
        • -
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        • F
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      • 18:30 ORD
        14:00 BRU
        12Hrs, 30m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 14:00 12h 30m 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 13:00
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 14:00
      • 12h 30m (3h 05m)
      • 1 Stop FRA · Frankfurt 3h 05m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1012)Airbus
      • United Airlines (UA 907)
        • -
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      • 18:30 ORD
        14:00 BRU
        12Hrs, 30m 1 Stop (FRA)
      • ORDChicago O'Hare International Airport 18:30 - BRU 14:00 12h 30m 1 Stop (FRA) Frankfurt
      • ORDChicago O'Hare International Airport 18:30
        FRAFrankfurt International Airport 13:00
      • FRAFrankfurt International Airport 09:55
        BRUBrussels Airport 14:00
      • 12h 30m (3h 05m)
      • 1 Stop FRA · Frankfurt 3h 05m
      • United Airlines (UA 907)Boeing Dreamliner Series 10
        Lufthansa (LH 1012)Airbus Industrie A320 Sharklets
      • United Airlines (UA 907)
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      • 18:35 ORD
        13:35 BRU
        12Hrs, 00m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:35 12h 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:20
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:35
      • 12h (3h 05m)
      • 1 Stop LHR · London 3h 05m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus
      • American Airlines (AA 86)
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      • 18:35 ORD
        13:40 BRU
        12Hrs, 05m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:40 12h 05m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:25
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:40
      • 12h 05m (3h 10m)
      • 1 Stop LHR · London 3h 10m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus
      • American Airlines (AA 86)
        • -
        • -
        • -
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        • F
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      • 18:35 ORD
        13:50 BRU
        12Hrs, 15m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:50 12h 15m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:35
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:50
      • 12h 15m (3h 20m)
      • 1 Stop LHR · London 3h 20m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus
      • American Airlines (AA 86)
        • -
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      • 18:35 ORD
        13:55 BRU
        12Hrs, 20m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:55 12h 20m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:40
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:55
      • 12h 20m (3h 25m)
      • 1 Stop LHR · London 3h 25m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus A321 Neo
      • American Airlines (AA 86)
        • -
        • -
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        • T
        • -
        • -
        • -
      • 18:35 ORD
        13:55 BRU
        12Hrs, 20m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:55 12h 20m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:40
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:55
      • 12h 20m (3h 25m)
      • 1 Stop LHR · London 3h 25m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus
      • American Airlines (AA 86)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 18:35 ORD
        13:55 BRU
        12Hrs, 20m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:55 12h 20m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:40
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:55
      • 12h 20m (3h 25m)
      • 1 Stop LHR · London 3h 25m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus
      • American Airlines (AA 86)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 18:35 ORD
        13:55 BRU
        12Hrs, 20m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 18:35 - BRU 13:55 12h 20m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 18:35
        LHRLondon Heathrow Airport 11:40
      • LHRLondon Heathrow Airport 08:15
        BRUBrussels Airport 13:55
      • 12h 20m (3h 25m)
      • 1 Stop LHR · London 3h 25m
      • American Airlines (AA 86)Boeing 787 9
        British Airways (BA 396)Airbus A320 Neo
      • American Airlines (AA 86)
        • M
        • -
        • -
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        • -
        • -
        • -
      • 19:05 ORD
        14:05 BRU
        12Hrs, 00m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:05 12h 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 12:50
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:05
      • 12h (2h 05m)
      • 1 Stop ZRH · Zurich 2h 05m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Embraer Emb E90
      • Swiss (LX 9)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 19:05 ORD
        14:05 BRU
        12Hrs, 00m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:05 12h 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 12:50
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:05
      • 12h (2h 05m)
      • 1 Stop ZRH · Zurich 2h 05m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Airbus A220 100 Passenger
      • Swiss (LX 9)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 19:05 ORD
        14:05 BRU
        12Hrs, 00m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:05 12h 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 12:50
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:05
      • 12h (2h 05m)
      • 1 Stop ZRH · Zurich 2h 05m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Embraer 190 E2
      • Swiss (LX 9)
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        • W
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        • -
      • 19:05 ORD
        14:10 BRU
        12Hrs, 05m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:10 12h 05m 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 12:55
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:10
      • 12h 05m (2h 10m)
      • 1 Stop ZRH · Zurich 2h 10m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Airbus A220 100 Passenger
      • Swiss (LX 9)
        • M
        • -
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        • -
        • -
      • 19:05 ORD
        14:10 BRU
        12Hrs, 05m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:10 12h 05m 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 12:55
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:10
      • 12h 05m (2h 10m)
      • 1 Stop ZRH · Zurich 2h 10m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Embraer Emb E90
      • Swiss (LX 9)
        • -
        • -
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        • -
        • -
        • -
        • S
      • 19:05 ORD
        14:35 BRU
        12Hrs, 30m 1 Stop (ZRH)
      • ORDChicago O'Hare International Airport 19:05 - BRU 14:35 12h 30m 1 Stop (ZRH) Zurich
      • ORDChicago O'Hare International Airport 19:05
        ZRHZurich Airport 13:20
      • ZRHZurich Airport 10:45
        BRUBrussels Airport 14:35
      • 12h 30m (2h 35m)
      • 1 Stop ZRH · Zurich 2h 35m
      • Swiss (LX 9)Airbus Industrie 330 300
        Swiss (LX 780)Airbus
      • Swiss (LX 9)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:10 ORD
        15:10 BRU
        13Hrs, 00m 1 Stop (CPH)
      • ORDChicago O'Hare International Airport 19:10 - BRU 15:10 13h 1 Stop (CPH) Copenhagen
      • ORDChicago O'Hare International Airport 19:10
        CPHCopenhagen Kastrup Airport 13:40
      • CPHCopenhagen Kastrup Airport 10:05
        BRUBrussels Airport 15:10
      • 13h (3h 35m)
      • 1 Stop CPH · Copenhagen 3h 35m
      • Scandinavian Airlines (SK 944)Airbus A359
        Scandinavian Airlines (SK 1593)Airbus A320 Neo
      • Scandinavian Airlines (SK 944)
        • M
        • -
        • -
        • T
        • -
        • -
        • S
      • 19:10 ORD
        16:55 BRU
        14Hrs, 45m 1 Stop (CPH)
      • ORDChicago O'Hare International Airport 19:10 - BRU 16:55 14h 45m 1 Stop (CPH) Copenhagen
      • ORDChicago O'Hare International Airport 19:10
        CPHCopenhagen Kastrup Airport 15:25
      • CPHCopenhagen Kastrup Airport 10:05
        BRUBrussels Airport 16:55
      • 14h 45m (5h 20m)
      • 1 Stop CPH · Copenhagen 5h 20m
      • Scandinavian Airlines (SK 944)Airbus A359
        Scandinavian Airlines (SK 1593)Airbus A320 Neo
      • Scandinavian Airlines (SK 944)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:15 ORD
        17:00 BRU
        14Hrs, 45m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 19:15 - BRU 17:00 14h 45m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 19:15
        LISLisbon Airport 13:15
      • LISLisbon Airport 09:05
        BRUBrussels Airport 17:00
      • 14h 45m (4h 10m)
      • 1 Stop LIS · Lisbon 4h 10m
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        TAP Air Portugal (TP 644)Airbus Industrie A330 200
      • TAP Air Portugal (TP 244)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 19:15 ORD
        17:30 BRU
        15Hrs, 15m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 19:15 - BRU 17:30 15h 15m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 19:15
        LISLisbon Airport 13:45
      • LISLisbon Airport 09:05
        BRUBrussels Airport 17:30
      • 15h 15m (4h 40m)
      • 1 Stop LIS · Lisbon 4h 40m
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        Brussels Airlines (SN 3816)Airbus
      • TAP Air Portugal (TP 244)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 19:40 ORD
        15:30 BRU
        12Hrs, 50m 1 Stop (DUB)
      • ORDChicago O'Hare International Airport 19:40 - BRU 15:30 12h 50m 1 Stop (DUB) Dublin
      • ORDChicago O'Hare International Airport 19:40
        DUBDublin Airport 12:50
      • DUBDublin Airport 09:00
        BRUBrussels Airport 15:30
      • 12h 50m (3h 50m)
      • 1 Stop DUB · Dublin 3h 50m
      • Aer Lingus (EI 124)Airbus Industrie A330 200
        Aer Lingus (EI 634)Airbus
      • Aer Lingus (EI 124)
        • -
        • -
        • -
        • T
        • -
        • S
        • -
      • 20:20 ORD
        17:05 BRU
        13Hrs, 45m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 20:20 - BRU 17:05 13h 45m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 20:20
        LISLisbon Airport 13:15
      • LISLisbon Airport 10:10
        BRUBrussels Airport 17:05
      • 13h 45m (3h 05m)
      • 1 Stop LIS · Lisbon 3h 05m
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        TAP Air Portugal (TP 644)Airbus
      • TAP Air Portugal (TP 244)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 20:20 ORD
        17:30 BRU
        14Hrs, 10m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 20:20 - BRU 17:30 14h 10m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 20:20
        LISLisbon Airport 13:45
      • LISLisbon Airport 10:10
        BRUBrussels Airport 17:30
      • 14h 10m (3h 35m)
      • 1 Stop LIS · Lisbon 3h 35m
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        Brussels Airlines (SN 3816)Airbus
      • TAP Air Portugal (TP 244)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 20:25 ORD
        17:05 BRU
        13Hrs, 40m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 20:25 - BRU 17:05 13h 40m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 20:25
        LISLisbon Airport 13:15
      • LISLisbon Airport 10:15
        BRUBrussels Airport 17:05
      • 13h 40m (3h)
      • 1 Stop LIS · Lisbon 3h
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        TAP Air Portugal (TP 644)Airbus A320 Neo
      • TAP Air Portugal (TP 244)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 20:25 ORD
        17:30 BRU
        14Hrs, 05m 1 Stop (LIS)
      • ORDChicago O'Hare International Airport 20:25 - BRU 17:30 14h 05m 1 Stop (LIS) Lisbon
      • ORDChicago O'Hare International Airport 20:25
        LISLisbon Airport 13:45
      • LISLisbon Airport 10:15
        BRUBrussels Airport 17:30
      • 14h 05m (3h 30m)
      • 1 Stop LIS · Lisbon 3h 30m
      • TAP Air Portugal (TP 244)Airbus A330 900 Neo
        Brussels Airlines (SN 3816)Airbus A320 Neo
      • TAP Air Portugal (TP 244)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 21:25 ORD
        16:05 BRU
        11Hrs, 40m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 16:05 11h 40m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 16:05
      • 11h 40m (1h 55m)
      • 1 Stop MUC · Munich 1h 55m
      • Lufthansa (LH 435)Airbus A359
        Lufthansa (LH 2288)Airbus
      • Lufthansa (LH 435)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 21:25 ORD
        16:05 BRU
        11Hrs, 40m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 16:05 11h 40m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 16:05
      • 11h 40m (1h 55m)
      • 1 Stop MUC · Munich 1h 55m
      • Lufthansa (LH 435)Airbus A359
        Lufthansa (LH 2288)Canadair Regional
      • Lufthansa (LH 435)
        • -
        • -
        • W
        • -
        • F
        • S
        • -
      • 21:25 ORD
        16:05 BRU
        11Hrs, 40m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 16:05 11h 40m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 14:40
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 16:05
      • 11h 40m (1h 55m)
      • 1 Stop MUC · Munich 1h 55m
      • Lufthansa (LH 435)Airbus A359
        Lufthansa (LH 2288)Airbus Industrie A320 Sharklets
      • Lufthansa (LH 435)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 21:25 ORD
        16:15 BRU
        11Hrs, 50m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 16:15 11h 50m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 14:50
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 16:15
      • 11h 50m (2h 05m)
      • 1 Stop MUC · Munich 2h 05m
      • Lufthansa (LH 435)Airbus A359
        Lufthansa (LH 2288)Canadair Regional
      • Lufthansa (LH 435)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 21:25 ORD
        16:15 BRU
        11Hrs, 50m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 16:15 11h 50m 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 14:50
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 16:15
      • 11h 50m (2h 05m)
      • 1 Stop MUC · Munich 2h 05m
      • Lufthansa (LH 435)Airbus A359
        Lufthansa (LH 2288)Airbus Industrie A320 Sharklets
      • Lufthansa (LH 435)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 21:25 ORD
        17:25 BRU
        13Hrs, 00m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 17:25 13h 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 16:05
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 17:25
      • 13h (3h 20m)
      • 1 Stop MUC · Munich 3h 20m
      • Lufthansa (LH 435)Airbus A359
        Brussels Airlines (SN 2646)Airbus
      • Lufthansa (LH 435)
        • -
        • -
        • -
        • T
        • -
        • S
        • S
      • 21:25 ORD
        17:25 BRU
        13Hrs, 00m 1 Stop (MUC)
      • ORDChicago O'Hare International Airport 21:25 - BRU 17:25 13h 1 Stop (MUC) Munich
      • ORDChicago O'Hare International Airport 21:25
        MUCMunich International Airport 16:05
      • MUCMunich International Airport 12:45
        BRUBrussels Airport 17:25
      • 13h (3h 20m)
      • 1 Stop MUC · Munich 3h 20m
      • Lufthansa (LH 435)Airbus A359
        Brussels Airlines (SN 2646)Airbus
      • Lufthansa (LH 435)
        • M
        • T
        • W
        • -
        • F
        • -
        • -
      • 16:30 ZRH
        12:50 MXP
        13Hrs, 20m 1 Stop (BRU)
      • ZRHZurich Airport 16:30 - MXP 12:50 13h 20m 1 Stop (BRU) Brussels
      • ZRHZurich Airport 16:30
        ORDChicago O'Hare International Airport 21:30
      • BRUBrussels Airport 17:50
        MXPMilan Malpensa Airport 12:50
      • 13h 20m (2h 40m)
      • 1 Stop BRU · Brussels 2h 40m
      • Swiss (LX 782)Embraer Emb E90
        United Airlines (UA 416)Boeing 787 8
      • Swiss (LX 782)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 21:45 ORD
        16:40 BRU
        11Hrs, 55m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 21:45 - BRU 16:40 11h 55m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 21:45
        LHRLondon Heathrow Airport 14:25
      • LHRLondon Heathrow Airport 11:30
        BRUBrussels Airport 16:40
      • 11h 55m (2h 55m)
      • 1 Stop LHR · London 2h 55m
      • British Airways (BA 296)Boeing Dreamliner Series 10
        British Airways (BA 398)Airbus
      • British Airways (BA 296)
        • -
        • T
        • W
        • -
        • -
        • -
        • S
      • 21:45 ORD
        16:40 BRU
        11Hrs, 55m 1 Stop (LHR)
      • ORDChicago O'Hare International Airport 21:45 - BRU 16:40 11h 55m 1 Stop (LHR) London
      • ORDChicago O'Hare International Airport 21:45
        LHRLondon Heathrow Airport 14:25
      • LHRLondon Heathrow Airport 11:30
        BRUBrussels Airport 16:40
      • 11h 55m (2h 55m)
      • 1 Stop LHR · London 2h 55m
      • British Airways (BA 296)Boeing Dreamliner Series 10
        British Airways (BA 398)Airbus
      • British Airways (BA 296)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
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      What’s the fastest flight time from Chicago to Brussels?

      The fastest flight time for direct flights from Chicago to Brussels is 8 hours . Check latest flight schedules & prices on Wego.

      What’s the most popular airline flying from Chicago to Brussels?

      The most popular airline flying from Chicago to Brussels is Turkish Airlines. Find the latest flight deals on Wego.

      How far is Brussels from Chicago?

      The flight distance between Chicago and Brussels is 6661km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 13:00. The last flight of the day departs at 18:00. See the full list of flight times on Wego.

      How many airlines offer direct flights from Chicago to Brussels?

      There are 1 airlines that offer direct flights from Chicago to Brussels. Find out the list of airlines on Wego.

      Popular Airlines flying from Chicago to Brussels

      Turkish Airlines ‏()

      Popular Destinations from Brussels

      Popular Destinations from Chicago

      Popular Hotels in Brussels

      Hotels In Popular Destinations